Hi Victoria -
This is definitely possible! There was a similar conversation that was started recently that I think you'd enjoy: https://community.canvaslms.com/message/203054-kindergarten-help
I think another thing that would really make a difference is the visuals throughout the course. You could create buttons with very clean and color-coded icons. That way, students know to press the book/red button to get to reading activities. If you use modules, you can use emojis (cut/paste or windows+.) to help students navigate.
For families, you can utilize headings on pages and activities. The Heading 2 settings with an icon in front of it will help everyone find the important parts of the materials. For example, a small lightbulb with the Objective heading could signify the main learning goals or a checkmark could show details about timeline etc. (I'd be happy to take a screenshot of something I do with my classes, if you'd like.)
On any page, you as an instructor can embed a video. I know it would take some time, but recording yourself or a teacher's aide with the instructions could be personal and help everyone know what to do. Even in the instructions at the end fo the video of "now press the 123/blue button to open our practice sheet" would allow students to feel pretty independent.
With any assignment, students can record audio or video to talk about submissions. Those comments can be replied to by you in the same way.
The Canvas Student app makes it pretty easy as well.
Let me know if you have any follow-up questions. While I teach grades 9-12, I have experience designing for littles too.
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