Until recently, I didn't even know this was possible. I knew that we are able to upload an image and hyperlink it, but apparently it is also feasible to hyperlink specific portions of an image. It takes a bit of prep work, working with pixels and HTML, but the final product is stellar. Disclaimer, HTML maps will likely not render well on mobile devices unless you ensure that the image is on the smaller side - perhaps 480 pixels wide. But if you ensure that students are on desktops or if you want to use this as a classroom activity on the projector then I invite you to explore. Check out the tutorial and links below.
Sean Nufer works collaboratively with the Instructional Design team and faculty to ensure utilization of state-of-the-art resources in the classroom.
He knows how to make gifs, but they're not very good.