Hello there, @NNPSLMS ...
On your "People" page, your course roster shows you which section each of your students is in. But, the "Groups" and "Group Set" areas that can be configured within the "People" page won't affect any students that are enrolled in various sections within your course. So, you should be all good. One way to confirm this on your own would be to log in to your school's "test" environment.
As the documentation indicates, this is a separate environment from your school's "production" environment (the environment that you typically log into every day). You could do all your testing there. Then, when you are comfortable with how you've set things up, log out of the "test" environment, and then log back in to your "production" environment to set up those same groups/group sets.
I hope this will help a bit. Let Community members know if you have any other questions about this...thanks! Take care, stay safe, and be well.
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