2 years and change later, but I found your post because the exact same thing happened to one of our profs.
What's more, any new links we inserted would wrap in a <span> with the screenreader CSS class. I had to edit the HTML, remove all the spans with that class, and then it finally started working as expected again. I've never seen anything like this, and cannot for the life of me figure out what triggered this to happen. I see nothing in the WYSWIG editor that sets it.
The only thing I can think is that it's coming from Ally:
He had copied a Zoom link from an old "Home" page, and pasted it on the page. He tends to copy a bit expansively and then delete what he doesn't want. I noticed to the right of an Ally icon there's a hidden span with this:
<span class="screenreader-only">
Accessibility score: Low
Click to improve
</span>
Maybe an invisible fragment stuck around?
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